Description
Amplopres AT is a combination drug consisting of Amlodipine Besylate and Atenolol. Amlodipine Besylate is a calcium channel blocker and is used in hypertension and prevents chest pain while Atenolol is a beta-blocker widely employed in hypertension, chest pain and post-heart attack. A fixed-dose combination of both the drugs produces enhanced anti-hypertensive effects. This dual combination is one of the most preferred antihypertensive drugs as it has excellent patient compliance and safety profile. Amlodipine Besylate and Atenolol are given in hypertension, chest pain and heart attack.
Amlodipine Besylate is a calcium channel blocker as it stops the influx of calcium ions through L type calcium channels. By inhibiting the entry of calcium channels, one can decrease the contractility of arterial smooth muscles and causes vasodilation. This all leads to relaxation of blood vessels and aids smooth arterial blood flow. In this way, it reduces the overall elevated blood pressure.
Atenolol binds with beta receptors present in the heart and vascular smooth muscles. It relaxes the blood vessels and lowers the blood pressure. It provides sufficient oxygen to the heart and other tissues. It helps in regulating proper heartbeat, therefore useful in a heart attack.


















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